Source link : https://health365.info/inhaled-farm-mud-alters-intestine-micro-organism-and-weakens-intestinal-barrier-in-mice/
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Breathing in agricultural mud might pose vital dangers to intestine well being for staff in animal agriculture, a College of California, Riverside, learn about has discovered.
Led by way of Declan McCole, a professor of biomedical sciences within the UCR Faculty of Medication, the learn about expands on prior findings that hog farm mud reasons airway irritation. The researchers now record within the Magazine of Carried out Toxicology that breathing in this mud additionally alters the intestine microbiome and impairs intestinal serve as, together with larger “leaky gut” or intestinal permeability. Leaky intestine is related to a spread of continual illnesses, together with inflammatory bowel illness, celiac illness, and kind 1 diabetes.
“Exposure to swine farm dust, which contains high levels of bacteria and endotoxins, caused both airway inflammation and increased passage of gut bacterial products into the bloodstream in our mouse models,” stated Meli’sa Crawford, a former postdoctoral researcher in McCole’s lab and the paper’s first creator. “But what’s especially striking is the impact we observed on the gut microbiome and metabolism.”
The researchers uncovered mice intranasally to hog mud extract for 3 weeks. The mice confirmed a vital drop in recommended bacterial species, together with Akkermansia muciniphila, Clostridium sp. ASF356, and Lachnospiraceae bacterium.
The analysis…
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Publish date : 2025-07-19 12:09:00
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