Oxidative Stress Marker May Signal Fracture Risk in T2D

Source link : https://www.newshealth.biz/health-news/oxidative-stress-marker-may-signal-fracture-risk-in-t2d/ TOPLINE: Elevated levels of plasma F2-isoprostanes, a reliable marker of oxidative stress, are associated with an increased risk for fractures in older ambulatory patients with type 2 diabetes (T2D) independently of…

Anxiety and Vomiting in Kids Undergoing Sedation in the ED

Source link : https://www.newshealth.biz/health-news/anxiety-and-vomiting-in-kids-undergoing-sedation-in-the-ed/ TOPLINE: Preprocedural anxiety levels among children undergoing procedural sedation and analgesia (PSA) with ketamine in the emergency department are not associated with the incidence of vomiting, according to a new study….

Malaria Vaccine Delivered by Mosquito Bite Shows Safety, Efficacy

Source link : https://www.newshealth.biz/health-news/malaria-vaccine-delivered-by-mosquito-bite-shows-safety-efficacy/ Immunization with a second-generation genetically attenuated parasite was safe and provided strong protection from malaria infection in young adults, a small clinical trial in the Netherlands suggested. Protective efficacy against malaria…

Trump Is Back: What This Could Mean for Health Policy

Source link : https://www.newshealth.biz/health-news/trump-is-back-what-this-could-mean-for-health-policy/ Gostin, Radhakrishnan, and Friedman are experts in health law and policy. The first Trump administration was marked by mismanagement of the COVID-19 pandemic and politicization of public health agencies. In 2020,…

New Agent for Biliary Tract Cancer Approved

Source link : https://www.newshealth.biz/health-news/new-agent-for-biliary-tract-cancer-approved/ The U.S. Food and Drug Administration (FDA) has approved zanidatamab (Ziihera, Jazz Pharmaceuticals, Inc.) as monotherapy for previously treated, unresectable or metastatic HER2-positive biliary tract cancer (BTC). This approval makes the…

Which Breast Cancer Patients Can Skip Postop Radiotherapy?

Source link : https://www.newshealth.biz/health-news/which-breast-cancer-patients-can-skip-postop-radiotherapy/ TOPLINE: The Profile for the Omission of Local Adjuvant Radiation (POLAR) biomarker, a 16-gene molecular signature, can help predict locoregional recurrence in patients with ER-positive early breast cancer following breast-conserving surgery…

FDA Approves Zanidatamab for Biliary Tract Cancer

Source link : https://www.newshealth.biz/health-news/fda-approves-zanidatamab-for-biliary-tract-cancer/ The FDA on Wednesday granted accelerated approval to zanidatamab (Ziihera), a bispecific antibody, for pretreated HER2-positive biliary tract cancer. Approval stipulates use in unresectable or metastatic cases, with HER2 positivity defined…

Diet’s Role in Parkinson’s Disease

Source link : https://www.newshealth.biz/health-news/diets-role-in-parkinsons-disease/ Interest is growing in the role of nutrition as means of slowing, or even preventing, neurodegeneration in patients with Parkinson’s disease (PD). For 15 years, John Duda, MD, national director of…

Novel Therapy Reduced Liver Fat, Improved Fibrosis in MASH

Source link : https://www.newshealth.biz/health-news/novel-therapy-reduced-liver-fat-improved-fibrosis-in-mash/ Patients with biopsy-confirmed metabolic dysfunction-associated steatohepatitis (MASH) and fibrosis who received a novel small molecule thyroid hormone receptor agonist achieved statistically significant reductions in liver fat, the phase IIb randomized VOYAGE…

Policy Experts Split on Dr. Oz Nomination to Lead CMS

Source link : https://www.newshealth.biz/health-news/policy-experts-split-on-dr-oz-nomination-to-lead-cms/ President-elect Donald Trump’s nomination of cardiothoracic surgeon and former talk show host Mehmet Oz, MD, to serve as Centers for Medicare & Medicaid Services (CMS) administrator has divided policy experts, with…

US Alcohol-Related Deaths Double in Two Decades

Source link : https://www.newshealth.biz/health-news/us-alcohol-related-deaths-double-in-two-decades/ TOPLINE: US alcohol-related mortality rates increased from 10.7 to 21.6 per 100,000 between 1999 and 2020, with the largest rise of 3.8-fold observed in adults aged 25-34 years. Women experienced a…

Deprescribe Low-Value Meds to Reduce Polypharmacy Harms

Source link : https://www.newshealth.biz/health-news/deprescribe-low-value-meds-to-reduce-polypharmacy-harms/ VANCOUVER, British Columbia — While polypharmacy is inevitable for patients with multiple chronic diseases, not all medications improve patient-oriented outcomes, members of the Patients, Experience, Evidence, Research (PEER) team, a group…

Canadian Survey Reveals Sexual Harassment in Medicine

Source link : https://www.newshealth.biz/health-news/canadian-survey-reveals-sexual-harassment-in-medicine/ In a new Medscape survey, nearly 1 in 10 Canadian physicians said they’ve personally experienced sexual abuse, harassment, or misconduct at their medical workplace during the past 3 years. Similarly, 9%…

Shoulder Pain Pointers for Primary Care

Source link : https://www.newshealth.biz/health-news/shoulder-pain-pointers-for-primary-care/ The causes of shoulder pain may be as common as a traumatic injury or as rare as a systemic inflammatory condition, according to the American Academy of Orthopaedic Surgeons. The combination…

How to Stop Bone Loss After Denosumab? No Easy Answers

Source link : https://www.newshealth.biz/health-news/how-to-stop-bone-loss-after-denosumab-no-easy-answers/ Patients who discontinue treatment with the osteoporosis drug denosumab, despite transitioning to zoledronate, show significant losses in lumbar spine bone mineral density (BMD) within a year, according to the latest findings…

Denosumab Raises Hypocalcemia Risk in Chronic Kidney Disease

Source link : https://www.newshealth.biz/health-news/denosumab-raises-hypocalcemia-risk-in-chronic-kidney-disease/ TOPLINE: Denosumab treatment for osteoporosis raises the risk for hypocalcemia, which worsens with advancing stages of chronic kidney disease (CKD), in those with CKD–Mineral and Bone Disorder (CKD-MBD) and in those…

Vagus Nerve Stimulation Proves Effective in Refractory RA

Source link : https://www.newshealth.biz/health-news/vagus-nerve-stimulation-proves-effective-in-refractory-ra/ WASHINGTON — An implantable vagus nerve stimulation (VNS) device effectively treats moderate to severe rheumatoid arthritis (RA) in patients who had previously failed at least one biologic or targeted synthetic disease-modifying…

When Appendicitis Recurs: Two Case Studies

Source link : https://www.newshealth.biz/health-news/when-appendicitis-recurs-two-case-studies/ Stump appendicitis is a rare complication that occurs when the residual appendix becomes inflamed after an appendectomy. It is estimated to occur in between 0.002% and 0.15% of cases, although it…

Checkpoint Inhibitors Seem Safe in Autoimmune Disease

Source link : https://www.newshealth.biz/health-news/checkpoint-inhibitors-seem-safe-in-autoimmune-disease/ WASHINGTON — Immune checkpoint inhibitor (ICI) therapy does not increase mortality in people with preexisting autoimmune diseases, new research has found. Results from a large database analysis of patients with and…